Therapy for sepsis: Einstein once said…

Management of Sepsis: The Surviving Sepsis Guidelines for Early Therapy

Hospital Physician June 2007 21 Sepsis is a common condition that is associated with poor patient outcomes and high financial costs. An estimated 750,000 cases of sepsis occur each year. Because sepsis is more common in elderly patients, its incidence is expected to rise as the US population ages.1 Despite recent advances in management and therapy, the mortality rate from severe sepsis remains ...

Informed consent in cardiac resynchronization therapy: what should be said?

Cardiac resynchronization therapy (CRT) for the treatment of heart failure (HF) raises complex problems for informed consent. CRT with and without defibrillator backup has been demonstrated in clinical trials to improve symptoms from HF and decrease mortality.1–4 A CRT pacemaker (CRT-P) may improve symptoms and reduce mortality in selected patients, even without offering the specific protection...

Sepsis: Antimicrobial Therapy

Medication Therapy for Early-Onset Neonatal Sepsis.

S sepsis is a common cause of morbidity and mortality in neonates. In a population-based surveillance study1 from 2005 to 2008, researchers estimated that 3300 cases of early-onset sepsis (EOS) occur in the United States each year, with 390 of these cases resulting in death. The risk is highest in preterm neonates, which account for 1570 of the 3300 cases and 360 deaths.1 Despite its prevalence...

Once-daily antiretroviral therapy: Spanish Consensus Statement.

BACKGROUND Administration of antiretroviral therapy (ART) once daily is creating extraordinary interest among the members of the scientific community and also among those who receive the therapy. However, in clinical practice, some doubts remain about its use. OBJECTIVES This document examines the characteristics and possibilities of treatment administered once daily. METHODS Consensus of 2...